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KMID : 0383820060610050473
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Tuberculosis and Respiratory Diseases
2006 Volume.61 No. 5 p.473 ~ p.478
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Two Cases of Transfusion Related Acute Lung Injury
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Lee Kyung-Joo
Kim Hye-Ok
Kim Jung-Ha
Ha Eun-Sil
Jung Jin-Yong
Lee Seung-Hyeun
Kim Se-Joong
Joo Moon-Kyung
Lee Eun-Joo
Kang Eun-Hae
Jung Ki-Hwan
Lee Sung-Yong
Lee Sang-Yeub
Kim Je-Hyeong
Shin Chol
Shim Jae-Jeong
In Kwang-Ho
Kang Kyung-Ho
Yoo Se-Hwa
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Abstract
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Transfusion related acute lung injury (TRALI) is a serious, potentially life-threatening complication of transfusion therapy that is sometimes under diagnosed and under reported. Patients with TRALI present with dyspnea/respiratory distress and fever. The symptoms, signs and chest radiological findings in TRALI are similar to transfusion associated circulatory overload, which makes it is difficult to distinguish it from circulatory overload. Although the mortality rate in cases of TRALI is relatively low, TRALI is the third most common cause of fatal transfusion reactions next to ABO blood type incompatibility and hepatitis. Mild-to-moderate cases of TRALI may be misdiagnosed as volume overload. Recently, we encountered two cases where the patients suffered from dyspnea and fever after a transfusion. and review of the relevant literature. (Tuberc Respir Dis 2006; 61: 473-478)
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KEYWORD
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Blood transfusion, Pulmonary reaction, Acute Lung injury, TRALI
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